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Themed collection Coronavirus articles - free to access collection

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Editorial

Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research

上证综指下跌6.85%,以科技版块为重点的深证综指下跌8.22%。
鉴于计算机编程被冠以“美国经济中尚未开垦的处女地”称号,纽约编程及设计学院正在努力让“谈论”代码变得更简单。到2020年,美国市场上将会有150万个计算机科学相关岗位,而计算机科学专业毕业生则仅有40万人。此外,计算机科学相关岗位在全美的平均增长率是其他职位的两倍。但是如果你并没有计算机科学专业学位,也没有计划重返校园又该如何呢?纽约编程及设计学院通过提供夜校课程和密集型研讨会的方式正在令学习网络设计和开发变得简单——从该项目毕业后,创建一家全新的网站,或是着手寻找技术相关的职位,并不是什么稀罕的事情。正如创始人杰瑞米?司乃帕(Jeremy Snepar)所言,在当下的数字化经济中,你不能不懂得怎样编程。他将编程看做是一种技术能力,一种能够也应该以更为简单的方式学习的能力,而纽约编程及设计学院正是为那些曾经感慨过“如果我懂怎样编程就好了”的人填补了一个重要的空白。

Graphical abstract: Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
Editorial

Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?

瑞典
The central government is aware of the danger of a property bubble that can inflate the national economy or even burst, derailing the ongoing economic recovery. Several policy measures have been announced to cool the red-hot real estate market. Well, how much trust do you place in government policies to control housing prices in 2010?

Graphical abstract: Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
Open Access Accepted Manuscript - Highlight

Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities

Open Access Perspective

Soft matter science and the COVID-19 pandemic

底特律居民都不会忘记1999年的暴风雪,当时多架飞机在底特律大都会国际机场的停机坪上滞留了数小时。同样,全美航空公司(US Airways)在2004年至2005年也遭遇了假日事故,当时超过72,000件行李丢失或损坏。

Graphical abstract: Soft matter science and the COVID-19 pandemic
Open Access Perspective

Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective

《江南Style》击败《Call Me Maybe》成为最受热捧的流行歌曲,而《007:天降杀机》战胜了《普罗米修斯》成为最多人查询的电影。

Graphical abstract: Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
Perspective

Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic

广义货币M2增长11.3%,低于13%左右的预期目标;
The movie takes place a year after the events of Finding Nemo and follows the journey of Dory to find her parents. Dory is helped by Nemo and Marlin in this epic adventure along the coast of California. You will also see some new characters introduced in the film.
时间:2009-10-22 编辑:vicki
Mr Cook has added three women to what was previously a white-male-dominated executive team and changed Apple’s board charter to commit to seeking out candidates from minorities when appointing directors.

Graphical abstract: Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
Perspective

Trends and targets in antiviral phototherapy

华盛顿暂时的“停战”能否持续?
北京正努力在年底前完成《区域全面经济伙伴关系协定》(Regional Comprehensive Economic Partnership,简称RCEP)。该协议长期以来被称为中国面对《跨太平洋伙伴关系协定》(Trans-Pacific Partnership agreement,简称TPP)的对策,以及代表了中国争取区域贸易霸权的努力。
Finding Dory releases on June 17, 2016.
SETTING: This house is in Kenwood, a neighborhood of 19th- and 20th-century Tudors, Mediterraneans, Victorians and colonial-style houses between Cedar Lake and Lake of the Isles, in the city’s Chain of Lakes. Roads are curving; sidewalks are lined with maple and ash trees. According to the listing agent, many of the neighborhood’s older houses have been restored, while houses built within the last 30 years have been torn down and replaced.

Graphical abstract: Trends and targets in antiviral phototherapy
Minireview

A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays

Although the original book got 7.9 out of 10 on Douban, the TV version only got 5 for its poor adaptation.

Graphical abstract: A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
Minireview

Novel biosensing methodologies for ultrasensitive detection of viruses

柯特妮韦弗(Courtney Weaver)

Graphical abstract: Novel biosensing methodologies for ultrasensitive detection of viruses
Application

Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug

“The headwinds that Chinese banks face will last for a long time,” he said. “In addition to lower sources for profit, they will also have to prepare themselves for losses on bad loans.”
5. Fred Hersch Trio “Floating” (Palmetto) The articulate grace of Fred Hersch’s current piano trio, with the bassist John Hébert and the drummer Eric McPherson, finds potent expression on an album structured like a nightclub set, with a few retooled standards mixed in with sturdy, emotionally transparent original songs.

Graphical abstract: Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
Open Access Review Article

ACE2 as a potential therapeutic target for pandemic COVID-19

China’s forex reserves — the world’s largest — have long been seen as the ultimate guarantor of financial stability, since they can be used to hedge against capital flight or to bail out domestic financial institutions struggling with a rise in bad debts.
7. Build a reputation.

Graphical abstract: ACE2 as a potential therapeutic target for pandemic COVID-19
Open Access Review Article

Diagnostic technologies for COVID-19: a review

王斌表示,去年母婴传播率也达到了历史最低点,从2012年的7.1%下降到2017年的4.9%。
两人的正式获奖词说的是表彰其“稳定匹配理论和市场设计实践”。

Graphical abstract: Diagnostic technologies for COVID-19: a review
From the themed collection: 雄安新区规划编制体系的创新实践
Open Access Review Article

Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review

You can read the full list of stories, but here are the top five:
The Turkish president said Angela Merkel, the German chancellor, was “no different from the Netherlands” and urged émigré Turks not to vote for “the government and the racists” in upcoming European elections. Ms Merkel faces a tough re-election bid in September.
crime罪行+al表名词,“人,物,状态”→犯罪分子
Once Upon A Time

Graphical abstract: Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
Open Access Review Article

An overview of key potential therapeutic strategies for combat in the COVID-19 battle

Recipient: His Royal Highness Prince Harry

Graphical abstract: An overview of key potential therapeutic strategies for combat in the COVID-19 battle
Open Access Review Article

Potential repurposed SARS-CoV-2 (COVID-19) infection drugs

《静待黎明》
他们现在对阵克里夫兰和波士顿时的人员对位看起来顺眼多了。

Graphical abstract: Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
Open Access Review Article

Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale

“我们会根据天气谨慎考虑投送的时间和地点,但这些都不会公开,”脱北者Park Sang-Hak说道,他曾经领导过一系列的气球投送运动。

Graphical abstract: Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
From the themed collection: 国企一季度税后净利润增18.6%
Review Article

In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections

当银行打电话给哈维尔的父母,告诉他们有关收费的事情的时候,他们才知道发生了这样的事情。

Graphical abstract: In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
Review Article

Antiviral drug discovery: broad-spectrum drugs from nature

Coca-Cola CEO Muhtar Kent
“他不在情报系统监视范围内,”总理补充道。
一个由8位《沃兹汽车》编辑组成的专家组在10月和11月评估了所有汽车车型使用的44款引擎,测试时间为日常上下班和周末在底特律都市区及附近进行的活动。各位专家根据多项特征进行打分,包括动力和扭矩、燃料经济、噪音、抖动和声振粗糙度、技术以及这些发动机相对于竞争对手的表现。
['?ltimit]

Graphical abstract: Antiviral drug discovery: broad-spectrum drugs from nature
Review Article

Influenza neuraminidase: A druggable target for natural products

May the season\'s joy fill you all the year round.
首尔坚称这些活动分子有派发单张的民主权利,但要求他们不要过度激怒北韩。
The US remains home to the biggest brands and the value of its top 10 increased by 10 per cent to $1.3tn in 2016. The top 10 UK brands, headed by Vodafone, lost 8 per cent of their value. Those in continental Europe — led by Germany’s SAP software group — rose 5 per cent. Finally, the $360bn value of Asia’s top 10 brands, headed by Tencent, China Mobile and Alibaba, was only 10 per cent lower than the value of the top 10 in continental Europe and the UK combined.
Meanwhile, domestic Internet users have formed a mobile payment habit, with the number of users making payments through smartphones skyrocketing to 469 million last year, up by 31.2 percent from the previous year.
冲击奖项:自从在特莱瑞德电影节首映以来,奥德曼一直就是最佳男主角奖项的宠儿。

Graphical abstract: Influenza neuraminidase: A druggable target for natural products
From the themed collection: 家居行业的暴利从哪儿来?
Critical Review

Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle

这枚奖牌拍出的高价远远超过了该拍卖行预计的成交金额——5万美元到10万美元。此前,仅有1903年诺贝尔和平奖奖牌在1985年被拍卖,拍得将近1.7万美元。
“今年榜单有趣的地方之一是,尽管网站都开始实行更严的密码设定政策,位数少的密码仍出现在今年的榜单上。”

Graphical abstract: Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
From the themed collection: 2017中国卫生洁具行业“喜与悲”
Critical Review

The role of biosensors in the detection of emerging infectious diseases

Ranking third on our Top-Grossing list is Steve Carell. Despicable Me 2 was a huge hit this year, bringing in $919 million at the box office. Overall, the franchise has earned $1.4 billion at the box office worldwide and a third movie, Minions, is on the way. Carell also appeared this year in the small indie The Way Way Back and The Incredible Burt Wonderstone. The latter failed to earn back its production budget at the box office but we’re only looking at ticket sales here — the film put another $22.5 million in Carell’s column for 2013.

Graphical abstract: The role of biosensors in the detection of emerging infectious diseases
Communication

Quantitative determination of mechanical stability in the novel coronavirus spike protein

"We are quite interested in looking at China's efforts and experience in combating corruption. It's a problem we are faced with in South Africa, and one we are tackling with a lot of vigor.Recently, the South African government introduced new measures to combat corruption. This is interesting, because it was immediately after a visit by our minister for public services, who met with the minister here who is responsible for anti-corruption measures.So this is one of the examples of the usefulness of this interaction between our leadership and the leadership of the People's Republic of China."

Graphical abstract: Quantitative determination of mechanical stability in the novel coronavirus spike protein
Communication

Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations

与无锡接近的涨幅第二的城市是湖南省省会长沙,该市环比涨幅为4.5%。
如果你是一个腼腆的人,那么一开始坐在前排可能会让你有点不自在。但是,我向你保证,这是接受老师传授的内容的最好的办法之一。你也可以听得更清楚。不用伸长脖子,你就可以看到黑板上所有的内容。
It makes piggybacks more comfortable.
Without the cut, Hollande would have earned 255,600 euros a year ($274,522), second only to Obama. Now he makes $198,700. Famously, his personal hairdresser makes $132,000 a year.

Graphical abstract: Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
Communication

MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling

prime
该校学员们称赞这里的训练将他们推出了自己的“舒适区”,还有针对他们各自企业情况量身定制的一对一辅导课程。“对于什么是优秀的领导,这里打开了我们的视界,”一位学员说,“我们先了解自己,了解我们的动力所在以及为什么,这样才能管理别人。”
再来看一下流失顾客的公司吧。
Baoneng’s raid has been bitterly resisted by Wang Shi, Vanke’s founder who has sought out white knights in a so far successful effort to retain control of the management-led company. The takeover battle fuelled a surge both in the price of Vanke’s Shenzhen-traded shares and Mr Yao’s known worth.

Graphical abstract: MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
Communication

Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses

3. 需求弹性。解决价格低迷的方法就是低价。这是老生常谈,而且适用于供需两个方面。超低的原油价格会刺激需求复苏吗?某些国家对石油市场控制较严,低油价可能不会延伸到零售领域。印尼等国已经取消成品油补贴,这有利于国家财政,但消费者得到的实惠将减少。不过,美国汽油价格已跌破每加仑2.40美元,与2014年中期相比,降幅超过了35%。而此番降价已带动汽油消费的攀升。2014年底,美国汽油日消费量创2007年以来新高。低价可以提升需求,而需求的增长则可带动油价反弹。
While the FT online and full-time MBAs are not strictly comparable because the criteria used to judge them are slightly different, it is interesting to note that IE and Warwick Business School are among six schools to feature in both rankings.

Graphical abstract: Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
Communication

Inhibition of SARS coronavirus helicase by bismuth complexes

7.The Renminbi's Devaluation
当然,这得取决于苹果是否能设法用更便宜的零部件、更慢的处理器、分辨率更低的屏幕、以及也许是塑料机身来造出一部330美元的iPhone。而用蒂姆?库克上周在高盛公司(Goldman Sachs)一次会议上的话说,它决不能是个“低劣产品”。
单词extend 联想记忆:
据中国电影监察机构日前表示,2016年中国票房总额有望超过2015年的440亿元人民币(折合68亿美元)。
In 2016, 1,576 foreigners became permanent Chinese residents, an increase of 163% on the previous year, according the Ministry of Public Security.

Graphical abstract: Inhibition of SARS coronavirus helicase by bismuth complexes
Open Access Edge Article

Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning

有些热门剧已经走得太远,应该降降温了,却仍在大张旗鼓,比如《唐顿庄园》(Downton Abbey)、《丑闻》(Scandal)和《复仇》(Revenge)。ABC频道的新剧《逍遥法外》(How to Get Away With Murder)是一部有趣的替代品,它是一部耸人听闻的夜间肥皂剧,讲述不法辩护律师的故事,简直可以称为“法律与无序”。
一定要展现自己过人的智慧,努力地表现出心神不定的样子。把那些社交技巧抛到脑后吧!
这是2015年1月11日发布在伊斯兰主义社交网站上的视频截图,显示了一个自称为AmedyCoulibaly的男人,声称就是他在2015年1月9日杀死了犹太超市的四个人质。

Graphical abstract: Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
Open Access Edge Article

A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers

Plenty of dark clouds loom over the U.S. job market -- particularly the potential double-punch of tax increases and spending cuts known as the fiscal cliff.[qh]
从2004年起,过去120年里的现代或当代艺术家们创作的10件作品在拍卖会上共卖出1亿多美元。而更早期绘画大师的作品价格则是稳中有跌。最近几周,这一趋势非常明显,伦敦的拍卖公司努力为自己的最新一批18世纪前绘画大师作品寻找买家。与近些年的情况一样,其中几乎没有名作。

Graphical abstract: A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
Open Access Edge Article

Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods

The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.

Graphical abstract: Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
From the themed collection: 提升上海城市能级和核心竞争力
Open Access Edge Article

Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors

By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.

Graphical abstract: Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
Open Access Edge Article

Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir

请接受我节日的祝贺。
反对:尽管该片被洛杉矶影评人协会评为最佳剪辑奖,但却没有受到纽约影评人的重视。它的势头会逐渐减弱吗?
The two pleasure devices both made of bronze date back more than 2000 years to China's Han Dynasty (206 BC–220 AD).

Graphical abstract: Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
Open Access Edge Article

Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes

For starters, breaches like that of Bitstamp and the much larger (valued at about $400 million at the time) 2011 hack of the exchange Mt. Gox are often misconstrued as security issues with the currency itself. But they are only signs of flaws in those particular exchanges and not a sign of an issue with the underlying technology. And it is the underlying technology behind bitcoin that most excites. As we wrote in the “Shape the Future” package of our January 2015 issue, most of the vocal enthusiasts so bullish on bitcoin—from big-name entrepreneurs like Marc Andreessen to the developers and miners who spend their days refreshing the bitcoin Reddit page—are more interested in the applications that can be built on bitcoin’s “block chain,” the currency’s foundational backbone, than they are in bitcoin as a monetary system. The block chain allows the secure exchange of any form of value between two entities.
mass
在赛场上,绰号Baby的天才逃亡车手(安塞尔?埃尔格特饰)依靠专属的音乐节奏开车而独占鳌头。与梦中女神(莉莉?詹姆斯饰)邂逅之后,Baby看到了希望,想与以往不堪的生活断个干干净净。Baby被迫为黑社会老大(凯文?史派西饰)干活,在派给他的最后一单中,危机一触即发。面前是巨大的挑战,对他的生活、爱人和自由来说,形势都岌岌可危……

Graphical abstract: Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
Accepted Manuscript - Paper

A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring

From the themed collection: 北京小升初明年将取消特长生招生
Open Access Paper

Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)

Recent years have seen a return of the bacterial infection, reaching numbers not seen since the 1960s, with admissions for a primary diagnosis more than doubling between 2010/11 and 2017/18, from 429 to more than 1,300.

Graphical abstract: Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
Paper

A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood

5.《出租车司机》

Graphical abstract: A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
Open Access Paper

Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations

翻译:译言网虽然面临全球经济衰退,但你依然能看到生生不息的Chanel,“我们依然非常赚钱,”Karl Lagerfeld坚定地说,他犀利的目光从墨镜后透射出来,好像这个事实就像埃
char茶,ity状态-请喝茶的状态-施舍-仁慈

Graphical abstract: Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
Open Access Paper

The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives

Likewise, if the 11 countries led by Japan left in the TPP manage to salvage a deal following the US exit that could provide some balance in the region.
单词stroke 联想记忆:
尽管詹姆斯和费德勒在工资和薪水上要少一些(相比于C罗和梅西),但是这两人去年的代言费是最高的,其中17次大满贯得主费德勒去年代言收入达到了4100万英镑。
A few people took advantage of technology:

Graphical abstract: The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
Open Access Paper

Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease

新兴市场出口额(以美元计算)下滑完全是一种价格效应,受到大宗商品价格下降的拖累。从数量上看,新兴市场出口自2014年以来一直持续上升,即便同比年增长率已放缓至2%左右——远远低于全球金融危机前后的两位数增长率,如第二张图表所示。
单词consciousness 联想记忆:

Graphical abstract: Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
Open Access Paper

Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro

一些智能的床会让你有更好的睡眠质量和睡眠姿势,但也会让你变成一个检查配偶是否出轨的私家侦探。除了检测这个床垫是否舒适,它会在有其他人占用你的床的时候提醒你。
"He (Premier Wen) underlined that China effectively countered the severe impact of the global financial crisis and has maintained steady and fast economic development. This allowed China to become the second-largest economy, almost doubling its GDP in five years."

Graphical abstract: Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
Open Access Paper

Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein

她解释说:“这一事件牵涉了许多方面,例如环境、能源、工作场所灾难和大国政府职能。它成为了人们焦虑情绪聚集的一个焦点。”

Graphical abstract: Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
Paper

Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide

你可能觉得夏威夷航空的运营相对容易,因为该公司的航班很少遇到美国大陆那种恶劣的天气条件。夏威夷航空公司在航班准点率排行榜上常年位居前列,在9月份最新公布的榜单上创下最高准点率。夏威夷航空公司最近宣布将把业务拓展到夏威夷岛外,开通从檀香山到北京的直达航班。
I empathize with the Mavs' position. It's tough to tell your fans that all hope is lost in November, and it's especially tough when you've got a Hall of Famer still on your roster.
The 2017 grads of Tsinghua University earn an average salary of 9,065 yuan per month, according to the survey released by xinchou.cn, an internet salary survey and report provider.
TextPride changed its name to Swyft Media and launched a platform that pushes emojis and stickers from new brands into messaging apps. Brands pay for the privilege, as they would with a regular ad campaign.

Graphical abstract: Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
Open Access Paper

Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses

Almost all of China’s gold goes to meet domestic demand, since companies are not allowed to export gold.
4.英国人似乎总是喜欢道歉,但道歉的意义并不相同。在英国,“对不起”实际可能表示这几种意思:(1)我没听清你说什么;(2)我没明白你的意思;(3)我听到了你说的,也明白你的意思,可我觉得你是个白痴。

Graphical abstract: Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
Open Access Paper

The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor

n. 道德,美德,品行,道德观
卓越雇主排名:66
美国国家海洋与大气管理局(National Oceanic and Atmospheric Administration)国家环境信息中心负责人托马斯愠尔(Thomas Karl)表示:“我们还是第一次看到这种情况。”

Graphical abstract: The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
From the themed collection: 房地产贷款风险可控
Open Access Paper

Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study

这个由财新赞助的系列指数,是基于对民营企业的调查得出的,样本数目也比官方PMI指数少得多,往往波动性更大。相比之下,官方PMI指数则主要关注规模更大的国有企业。
vi. 流通,循环,传播
“目前市场上有大量尖端,环保的人造皮草,我相信你会同意现在没有任何借口来杀死动物以获取皮草了。”

Graphical abstract: Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
Open Access Paper

Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework

沙特王储穆罕默德·本·萨勒曼表示,多数被捕人员已同意归还部分非法获得的钱财,以换取自由。
他说:“国内需求增长太慢,而新增出口订单的增幅又放缓至5个月内的低点……我们依然预计(中国政府)会推出进一步货币和财政宽松举措,以抵消经济增长的下行风险。”

Graphical abstract: Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
Open Access Paper

Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach

Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.

Graphical abstract: Several coumarin derivatives and their Pd(ii) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
Open Access Paper

Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors

Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.

Graphical abstract: Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
Open Access Paper

Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins

Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.

Graphical abstract: Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
From the themed collection: 不必为土地出让金下降担忧
Open Access Paper

Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform

In some ways, Life Is Strange couldn’t be more different than Dontnod Entertainment’s sci-fi action game Remember Me, but in other ways, the episodic adventure game is similar. Both games use Unreal Engine 3 technology to create beautiful worlds to explore. And both titles also feature a strong female protagonist. Set in Arcadia Bay, Oregon, players take control of teenager Max Caulfield and embark on an adventure that will span five interactive episodes.
Index: 100.0
这表明,一般而言,大学教育从长期看来收益良多。

Graphical abstract: Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
Open Access Paper

A modular microarray imaging system for highly specific COVID-19 antibody testing

法国电信商学院(Télécom Business School)和布拉格经济大学(University of Economics)的教师性别比例最为均衡,女教师占50%,瑞士苏黎世大学(University of Zurich)的教师性别比例最不均衡,女教师仅为9%。瑞士洛桑国际管理发展学院(IMD)的教师队伍国际化程度最高,94%来自海外,米兰理工大学MIP管理学院的教师则均为意大利人。
The ranking is in part based on how successful alumni have been in their careers, as reflected in the salary data.

Graphical abstract: A modular microarray imaging system for highly specific COVID-19 antibody testing
Open Access Paper

Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms

6. 查理兹-塞隆 1650万美元
9.你会一直回避你的老板。
在中国永久居留的外国人在投资、购房、受教育等方面享受中国公民同等待遇。

Graphical abstract: Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
Open Access Paper

Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening

单词exceed 联想记忆:

Graphical abstract: Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
Open Access Paper

Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations

A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.

Graphical abstract: Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
Open Access Paper

Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets

随着美国电子商务交易接近零售总额的10%,越来越多的商家开始寻找既好用又能帮他们快速卖出商品的电商平台。
hub

Graphical abstract: Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
Open Access Paper

A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation

Baoneng’s raid has been bitterly resisted by Wang Shi, Vanke’s founder who has sought out white knights in a so far successful effort to retain control of the management-led company. The takeover battle fuelled a surge both in the price of Vanke’s Shenzhen-traded shares and Mr Yao’s known worth.
adj. 浓缩的;扼要的 vt. 浓缩(condense

Graphical abstract: A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
Open Access Paper

An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19

3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.

Graphical abstract: An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
Open Access Paper

Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies

Mini-Series or Movie: “The People v. O. J. Simpson: American Crime Story” (FX)
The diplomatic row began when Ankara’s foreign minister was denied entry to the Netherlands on Saturday for a campaign rally in favour of Mr Erdogan’s constitutional reforms. Armed Dutch police also intercepted another Turkish minister, Fatma Betul Sayan Kaya, on her way to the rally in Rotterdam and escorted her back to the German border.

Graphical abstract: Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
From the themed collection: 城乡融合发展纲领性文件重磅出炉
Paper

Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material

It's real easy for us to sit up here and tell teams that they need to go out there and lose a bunch of games. We're not the ones on the hook for ticket sales and advertisers.
[.k?lkju'lein]

Graphical abstract: Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
Open Access Paper

A facile assay for rapid detection of COVID-19 antibodies

“这是我们租户运动生死攸关的时刻,”大都会住宅委员会(Metropolitan Council on Housing)的项目总监伊拉娜·迈尔(Ilana Maier)说,“如果我们现在不能大举强化规定,那么这些政策在十年内都发挥不了作用。”

Graphical abstract: A facile assay for rapid detection of COVID-19 antibodies
Open Access Paper

Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses

对于韩国部署萨德的决定,中国政府已经以越来越大的愤怒加以回应。尽管韩国坚称该系统旨在保护韩国免受朝鲜导弹的打击,中国却担心该技术会令这个美国的盟国查探中国的军事动向。
最糟糕地利用社交媒体奖
FlightAware以航班跟踪应用程序而为旅行者所熟知,从2010年到2012年,这家网站按照美国交通部的规定,统计了感恩节和冬季假期(圣诞节至新年)旅行期间美国18家大航空公司和地区航空公司的航班延误情况。
Indeed, their ability to do so peacefully is among their strengths.

Graphical abstract: Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
Open Access Paper

Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2

An industry insider said the survey indicated that China was in the process of an industrial upgrade and a high value-added service sector was on the rise. This is leading to a thriving Internet industry, which needs science and engineering professionals, and a booming finance industry, which requires finance and economics professionals.

Graphical abstract: Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
From the themed collection: 陶瓷卫浴市场六大黑幕令人忧
Open Access Paper

Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease

三星的声明则更加简短:“媒体对收购的报道毫无根据。”
中国最高质量监督部门日前表示,去年通过网购平台出口到中国的消费品,超过40%是不合格的。
Thus assuming that type D personalities lack social interest is not correct but the right thing is that they might be interested in people but afraid to approach them because they fear rejection.

Graphical abstract: Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
From the themed collection: 27日港股内房板块再度大涨
Open Access Paper

Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19

正如这届美国政府中一切与贸易有关的事项一样,韩美贸易协定(Korus)的未来也不可避免地引发了激烈辩论。本届政府内部强烈反对退出该协议的是特朗普安全团队,他们认为在一场地缘政治危机期间切断与重要盟友的贸易纽带很可能不是个好主意。美国企业也不支持退出。这两股力量都可能意味着美国政府至少在短期内不会发出任何威胁。但是话又说回来,首尔方面的政治局势也不稳定。韩国新政府是否可能行使自己退出协定的权利呢?
《临床心理学》在2012年刊登的一篇研究文章中凸显了设身处地的作用。不管当事人有没有记忆方面的问题,这个方法都能够提高他们的提高记忆能力。和其他针对人类记忆的研究一样,科学家们要求参与者们记忆一个关于人格特点的单词表。参与者被要求使用特定的、能够帮助他们回忆的方法。比如有些参与者用谐音记忆,有些联想这个特征的定义,有一些则用“设身处地法”,把自己想象成那么一个人。

Graphical abstract: Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
Paper

Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties

总排名76位的新加坡管理大学(Singapore Management University)李光前商学院(Lee Kong Chian School of Business)是首家进入这一排行榜的新加坡商学院。今年共7家亚洲商学院上榜。李光前商学院校友在亚洲商学院中最具国际流动性。他们在流动性指标方面排名第25,比在亚洲商学院中流动性排第二的台湾国立中山大学(National Sun Yat-Sen University)高57位。
10.Meditate

Graphical abstract: Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
Open Access Paper

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.

Graphical abstract: Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
From the themed collection: 泉州成为我国援非建材的主要产地
Paper

Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract

3.Porto, Portugal

Graphical abstract: Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
Open Access Paper

Anti-HIV drug repurposing against SARS-CoV-2

4.美国电话电报公司
尽管当下是一个全球性的经济环境,但仅有约20%的美国人会说第二门语言。Sixty Vocab的目标就是以其在线外语游戏改变这一现状。基于2000个单词相当于一门外语的六成精髓的假设,Sixty Vocab试图使学习必要词汇的过程变得有趣。这些在线游戏能教你在对话中最为常用的词汇,并辅以限制时间的规则——你在越短的时间内猜出单词,你就能越快地进入到下一个阶段。Sixty Vocab填补了你高中课程和昂贵外语学习项目之间的空白,为那些想要在早餐咖啡或通勤时间学习一门外语的人提供了一个独一无二的选择。
2018年它们会拿出更多创造力,包括在非现金效益上的创造力。例如,美国银行(Bank of America)刚刚引入了一项新计划,让全球银行业务和市场部门的员工休至多6周的长假。该计划是有条件的:员工必须在该行工作至少10年,每5年可以申请一次长假,最多享受3次。但根据英国《金融时报》看到的一份内部备忘录,首席运营官汤姆蒙塔格(Tom Montag)鼓励符合条件的员工考虑该计划。

Graphical abstract: Anti-HIV drug repurposing against SARS-CoV-2
Paper

Length-scale dependence of protein hydration-shell density

wheat
In the ranking of finance programmes for students already working in the industry, London Business School regains the top place it occupied between 2011 and 2015, while Judge Business School at Cambridge university drops back into second place.
其他的欧洲国家生活成本在增长,排名有进步。伦敦上升了5个名次,并且进入前十。
编者案:伦敦奥运会开幕在即,让我们来看看本届奥运会都有哪些比赛项目吧,同时在看看的同时也不要忘了学学比赛项目的词汇,一举两得何乐而不为呢?

Graphical abstract: Length-scale dependence of protein hydration-shell density
Open Access Paper

High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus

In one tweet that was posted on Jan 10, Obama wrote, "Thank you for everything. My last ask is the same as my first. I'm asking you to believe - not in my ability to create change, but in yours."
Closer to home, fake official data are just as prevalent. The UK’s Office for National Statistics on Tuesday reported that British inflation, measured by its longstanding retail prices index, rose to 4.1 per cent in December. This number is nonsense and the ONS knows it. It tells people the RPI “does not meet the required standard” to be given a quality stamp, yet it has refused since 2012 to take steps to improve the measure and bring it closer to the lower headline measure of 3 per cent.

Graphical abstract: High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
From the themed collection: 警方打掉“套路贷”敲诈勒索团伙
Paper

A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor

Rank: 2
俄罗斯把自己看作超级大国 -- 这在国内是毋庸置疑的。
The Internet users posted screenshots from social networking apps showing questions and answers that were going to be on the exam.

Graphical abstract: A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
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据中央电视台报道,她的妈妈在1月30日才发现了此事。
你可能已经在使用谷歌日历了,但你使用的方式是否正确呢?告诉你一个秘诀:只要把在那个日子和那个时候会真正发生的事情记录在谷歌日历上就行。同时利用iPhone提醒记住那些时间敏感性不太强的事情(即不是那些精确到小时和分钟的事情)。遵循这一战略有助于你保持更清醒的状态。

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